170 research outputs found

    Bose IR Reception Test Improvements

    Get PDF
    This Major Qualifying Project was completed in conjunction with Bose Corporation to develop a robust, qualitative, and repeatable test procedure to qualify the Infrared Systems for products within BoseÂ’s Consumer Electronics Division. The test procedure will reduce the current measurement error by 50% and decrease the test time to 1/4 the time of the current procedure. Through data analysis, fixture development, and process qualifying, a final procedure was developed and recommendations were developed. Based on design criteria, this project proposes a method to set up, record, and evaluate BoseÂ’s Infrared System for any past, current, and future product

    Banksia Gardens Community Centre B14: After-School Computer Club

    Get PDF
    Banksia Gardens Community Centre is located in Broadmeadows, the most disadvantaged suburb of Victoria, Australia. Disadvantaged communities are at a great risk of lagging behind as the world incorporates more computer-based resources into daily life and the workforce. The goal of our project was to motivate and enable the children at the center to pursue worthwhile uses of technology by providing an engaging way to learn computer science concepts in their after-school club. We also performed a technological needs assessment with solutions to improve the center\u27s services. From our achievements and the center’s continued effort to further computer science and technology, the residents of Broadmeadows now have a place to learn technological skills that are necessary in the modern world

    Operationalizing Frailty in the Atherosclerosis Risk in Communities Study Cohort

    Get PDF
    Background: Factors that may contribute to the development of frailty in late life have not been widely investigated. The Atherosclerosis Risk in Communities (ARIC) Study cohort presents an opportunity to examine relationships of midlife risk factors with frailty in late life. However, we first present findings on the validation of an established frailty phenotype in this predominantly biracial population of older adults. Methods: Among 6,080 participants, we defined frailty based upon the Cardiovascular Health Study (CHS) criteria incorporating measures of weight loss, exhaustion, slow walking speed, low physical activity, and low grip strength. Criterion and predictive validity of the frailty phenotype were estimated from associations between frailty status and participants' physical and mental health status, physiologic markers, and incident clinical outcomes. Results: A total of 393 (6.5%) participants were classified as frail and 50.4% pre-frail, similar to CHS (6.9% frail, 46.6% pre-frail). In age-adjusted analyses, frailty was concurrently associated with depressive symptoms, low self-rated health, low medication adherence, and clinical biomarker levels (ie, cholesterol, hemoglobin A1c, white blood cell count, C-reactive protein, and hemoglobin). During 1-year follow-up, frailty was associated with falls, low physical ability, fatigue, and mortality. Conclusions: These findings support the validity of the CHS frailty phenotype in the ARIC Study cohort. Future studies in ARIC may elucidate early-life exposures that contribute to late-life frailty

    Upper limb prostheses: bridging the sensory gap

    Get PDF
    Replacing human hand function with prostheses goes far beyond only recreating muscle movement with feedforward motor control. Natural sensory feedback is pivotal for fine dexterous control and finding both engineering and surgical solutions to replace this complex biological function is imperative to achieve prosthetic hand function that matches the human hand. This review outlines the nature of the problems underlying sensory restitution, the engineering methods that attempt to address this deficit and the surgical techniques that have been developed to integrate advanced neural interfaces with biological systems. Currently, there is no single solution to restore sensory feedback. Rather, encouraging animal models and early human studies have demonstrated that some elements of sensation can be restored to improve prosthetic control. However, these techniques are limited to highly specialized institutions and much further work is required to reproduce the results achieved, with the goal of increasing availability of advanced closed loop prostheses that allow sensory feedback to inform more precise feedforward control movements and increase functionality

    Predictors of Workplace Bullying and Cyber-Bullying in New Zealand

    Get PDF
    Background: The negative effects of in-person workplace bullying (WB) are well established. Less is known about cyber-bullying (CB), in which negative behaviours are mediated by technology. Drawing on the conservation of resources theory, the current research examined how individual and organisational factors were related to WB and CB at two time points three months apart. Methods: Data were collected by means of an online self-report survey. Eight hundred and twenty-six respondents (58% female, 42% male) provided data at both time points. Results: One hundred and twenty-three (15%) of participants had been bullied and 23 (2.8%) of participants had been cyber-bullied within the last six months. Women reported more WB, but not more CB, than men. Worse physical health, higher strain, more destructive leadership, more team conflict and less effective organisational strategies were associated with more WB. Managerial employees experienced more CB than non-managerial employees. Poor physical health, less organisational support and less effective organisational strategies were associated with more CB. Conclusion: Rates of CB were lower than those of WB, and very few participants reported experiencing CB without also experiencing WB. Both forms of bullying were associated with poorer work environments, indicating that, where bullying is occurring, the focus should be on organisational systems and processes

    The Angular Correlation Function of Galaxies from Early SDSS Data

    Get PDF
    The Sloan Digital Sky Survey is one of the first multicolor photometric and spectroscopic surveys designed to measure the statistical properties of galaxies within the local Universe. In this Letter we present some of the initial results on the angular 2-point correlation function measured from the early SDSS galaxy data. The form of the correlation function, over the magnitude interval 18<r*<22, is shown to be consistent with results from existing wide-field, photographic-based surveys and narrower CCD galaxy surveys. On scales between 1 arcminute and 1 degree the correlation function is well described by a power-law with an exponent of ~ -0.7. The amplitude of the correlation function, within this angular interval, decreases with fainter magnitudes in good agreement with analyses from existing galaxy surveys. There is a characteristic break in the correlation function on scales of approximately 1-2 degrees. On small scales, < 1', the SDSS correlation function does not appear to be consistent with the power-law form fitted to the 1'< theta <0.5 deg data. With a data set that is less than 2% of the full SDSS survey area, we have obtained high precision measurements of the power-law angular correlation function on angular scales 1' < theta < 1 deg, which are robust to systematic uncertainties. Because of the limited area and the highly correlated nature of the error covariance matrix, these initial results do not yet provide a definitive characterization of departures from the power-law form at smaller and larger angles. In the near future, however, the area of the SDSS imaging survey will be sufficient to allow detailed analysis of the small and large scale regimes, measurements of higher-order correlations, and studies of angular clustering as a function of redshift and galaxy type

    A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans

    Get PDF
    T cells are classically recognized as distinct subsets that express αβ or γδ TCRs. We identify a novel population of T cells that coexpress αβ and γδ TCRs in mice and humans. These hybrid αβ-γδ T cells arose in the murine fetal thymus by day 16 of ontogeny, underwent αβ TCR–mediated positive selection into CD4+ or CD8+ thymocytes, and constituted up to 10% of TCRδ+ cells in lymphoid organs. They expressed high levels of IL-1R1 and IL-23R and secreted IFN-γ, IL-17, and GM-CSF in response to canonically restricted peptide antigens or stimulation with IL-1β and IL-23. Hybrid αβ-γδ T cells were transcriptomically distinct from conventional γδ T cells and displayed a hyperinflammatory phenotype enriched for chemokine receptors and homing molecules that facilitate migration to sites of inflammation. These proinflammatory T cells promoted bacterial clearance after infection with Staphylococcus aureus and, by licensing encephalitogenic Th17 cells, played a key role in the development of autoimmune disease in the central nervous system

    Crop Updates 2007 - Weeds

    Get PDF
    This session covers thirty two papers from different authors: 1. ACKNOWLEDGEMENTS, Alexandra Douglas CONVENOR – WEEDS DEPARTMENT OF AGRICULTURE AND FOOD WILD RADISH MANAGEMENT 2. Decimate a wild radish seed bank in five years, Peter Newman, Sally Peltzer, Abul Hashem and Aik Cheam, Department of Agriculture and Food 3. High level of seed-set control in wild radish is achievable, Aik Cheam and Siew Lee,Department of Agriculture and Food 4. Wild radish: Best management practice, Aik Cheam and Siew Lee, Department of Agriculture and Food 5. Control of phenoxy resistant wild radish through the combined effects of wheat competition and phenoxy herbicides, Natalie Maguire and Michael Walsh, WAHRI, School of Plant Biology, University of Western Australia 6.Efficacy of florasulam on chlorsulfuron resistant and susceptible wild radish populations in Western Australia, Michael Walsh1 and Dan Cornally2, 1WAHRI, School of Plant Biology, University of Western Australia, 2Dow Agrosciences Australia 7. Does liming to increase soil pH limit the growth and development of wild radish (Raphanus raphanistrum)Matt Willis and Michael Walsh, WAHRI, School of Plant Biology, University of Western Australia IWM TECHNIQUES AND SEEDBANKS 8. Weed trimming – a potential technique to reduce weed seed set, Glen Riethmuller, Abul Hashem and Shahab Pathan, Department of Agriculture and Food 9. Burn narrow windrows in the wind, Peter Newman1and Michael Walsh2, 1Department of Agriculture and Food, 2Research Fellow, WA Herbicide Resistance Initiative 10. Winning the Weed War with the Weed Seed Wizard! Michael Renton, Sally Peltzer and Art Diggle, Department of Agriculture and Food HERBICIDE RESISTANCE AND GENE FLOW 11. Frequency of herbicide resistance in wild oat (Avena fatua) across the Western Australian wheatbelt, Mechelle Owen and Stephen Powles, WA Herbicide Resistance Initiative, School of Plant Biology, University of Western Australia 12. Pollen mediated gene flow of herbicide resistance can occur over long distances doe annual ryegrass (Lolium rigidum): Results of two years with different meteorological conditions, Roberto Busi, Robert Barrett-Lennard and Stephen B. Powles, Western Australian Herbicide Resistance Initiative, School of Plant Biology – University of Western Australia 13. Doublegee has developed resistance to metsulfuron-methyl within WA wheatbelt, Dr Abul Hashem1and Dr Shahab Pathan2, 1Senior Research Officer, and 2Research Officer, Department Agriculture and Food 14. Another case of glyphosate resistance in annual ryegrass confirmes within Western Australia, Dr Abul Hashem1and Dr Shahab Pathan2, 1Senior Research Officer, and 2Research Officer, Department Agriculture and Food 15. Glyphosate resistance in the northern NSW – implications for Western Australian farming systems, Andrew Storrie, Tamworth Agricultural Institute, NSW Department of Primary Industries ALTERNATIVES TO TRIFLURALIN, KNOCKDOWNS, TANK MIXES AND NOVEL USES 16. Alternative pre-emergent herbicides to trifluralin for annual ryegrass control, Mr David Minkey and Dr Abul Hashem, Department of Agriculture and Food, 17. Evaluation of a new pre-emergent herbicide alternative dor the control of trifluralin resistant Lolium rigidum Gaudin (annual ryegrass) in wheat and barley, Craig A. Ruchs, Syngenta Crop Protection Australia Pty Ltd and Dr Peter Boutsalis, University of Adelaide 18. Novel knockdown tank mixes: Results from 12 trials over four years, Shahab Pathan1, Abul Hashem2, Catherine Borger3, Nerys Wilkins and Julie Roche, Department of Agriculture and Food, Western Australia, and 3the University of Western Australia 19. Alternative herbicides for weed control in lupins, Peter Newman and Martin Harries, Department of Agriculture and Food 20. Novel use application of clopyealid in lupins, John Peirce, and Brad Rayner, Department of Agriculture and Food 21. A model to predict grass selective herbicide rates, John Moore, Department of Agriculture and Food CROP AND WEED MANAGEMENT 22. Inter-row weed control in wide row lupin using knockdown-based tank mixes, Dr Abul Hashem1, Ray Fulwood2 and Chris Roberts3, 1Senior Research Officer, Department of Agriculture and Food, 2Farmer, Meckering, WA, 3Technical Officer, Department of Agriculture and Food 23. Timing of weed removal in wide-row lupins, Sally Peltzer, Shahab Pathan and Paul Matson, Department of Agriculture and Food 24. The effect of row spacing and crop density on competitiveness of lupins with wild radish, Bob French and Laurie Maiolo, Department of Agriculture and Food 25. Is delayed sowing a good strategy for weed management in lupins? Bob French, Department of Agriculture and Food 26. Delayed sowing as a strategy to manage annual ryegrass, Department of Agriculture and Food HERBICIDE TOLERANCE 27. The effect of herbicides on nodulation in lupins, Lorne Mills1, Harmohinder Dhammu2 and Beng Tan1, 1Curtin University of Technology, and 2Department of Agriculture and Food 28. Response of new wheat varieties to herbicides, Harmohinder Dhammu, Department of Agriculture and Food 29. Herbicide tolerance of new barley varieties, Harmohinder Dhammu, Vince Lambert and Chris Roberts, Department of Agriculture and Food 30. Herbicide tolerance of new oat varieties, Harmohinder Dhammu, Vince Lambert and Chris Roberts, Department of Agriculture and Food OTHER WEEDY MATTERS 31. Research and extension need for wild radish and other cruciferous weeds, Aik Cheam, Department of Agriculture and Food 32. e-weed – an information resource of seasonal weed management issues, Vanessa Stewartand Julie Roche, Department of Agriculture and Foo

    International Veterinary Epilepsy Task Force consensus proposal: Medical treatment of canine epilepsy in Europe

    Get PDF
    In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug treatment protocols, 1) is based on current published evidence-based literature, 2) considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and 3) reflects the authors’ experience. With this paper it is aimed to provide a consensus for the management of canine idiopathic epilepsy. Furthermore, for the management of structural epilepsy AEDs are inevitable in addition to treating the underlying cause, if possible

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

    Get PDF
    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
    corecore